protean manifestations

He had a verrucous epidermal nevus involving the right axilla (figure 1B). Our clinical experience enables us to concur with the recommendations of Agatstein and Stabile' concerning their management. Clinicians and clinical investigators have sometimes assumed that an interaction between drugs occurs through one specific, discrete mechanism, such as displacement of a drug from plasma protein binding sites by an interacting drug or by inhibition of the metabolism of one drug by another. The burden of celiac disease alleviates with gluten-free diet. Our experience with eight neonates emphasizes the protean manifestations of this disease. PURPOSE: Mitochondrial abnormalities are major causes of human disease. Proteus had the gift of prophecy. From the Department of Epidemiology and Environmental Health, University of Vermont College of Medicine, Burlington. One variant (Group A) consisted of six patients who had a mild form of non-progressive pneumonia with minimum extra-pulmonary involvement. The major features are related to hemolytic anemia and vaso-occlusion, which can lead to acute and chronic pain and tissue ischemia or infarction. Corresponding Author. Granulomatous angiitis is an uncommon necrotising vasculitis of unknown cause restricted to vessels of the central nervous system. Authors Neslihan Eşkut 1 . an | \ ˈprōt-ē-ən \ Medical Definition of protean (Entry 2 of 2) T2 - Protean manifestations of a rare upper respiratory disorder revisited. Clinical manifestations are most . The protean manifestations of childhood narcolepsy and their misinterpretation The protean manifestations of childhood narcolepsy and their misinterpretation Stores, Gregory 2006-04-01 00:00:00 Narcolepsy often begins in childhood but is infrequently recognized, partly because of its many manifestations that can be confused with other conditions. And the worst part is, the symptoms can be deceiving. Intravenous drug use is an increasing social problem. "Leptospirosis" is the disease produced by any of the group of spirochetes known as Leptospirae. J Pediatr Hematol Oncol. Despite the increasing frequency with which . Its epidemiology has changed, with the majority of cases now primarily affecting adolescents and adults. Physical examination revealed a right-sided frontal bulge (figure 1A). Granulomatous angiitis is an uncommon necrotising vasculitis of unknown cause restricted to vessels of the central nervous system. Any type of vessel in any tissue may be affected. Among the protean neurological manifestations of VZV vasculopathy are aneurysm, subarachnoid and cerebral haemorrhage, arterial ectasia, and carotid dissection. Mumps has re-emerged as an infection in the developed world. Local anesthetic systemic toxicity is a potentially lethal condition with protean manifestations, and anesthesiologists must understand its risks, prevention, and safe management. Medical Progress from The New England Journal of Medicine — The Cytomegaloviruses: Ubiquitous Agents with Protean Clinical Manifestations — (First of Two Parts) The event can be recorded and made available for viewers to watch at their convenience as an on-demand video . Neurolymphomatosis. Multiple neurologic complications may follow the reactivation of varicella-zoster virus (VZV), including herpes zoster (also known as zoster or shingles), postherpetic neuralgia, vasculopathy, myelitis, necrotizing retinitis, and zoster sine herpete (pain without rash). Fauci also emphasized that the virus's "protean manifestations" have been interesting and unique to the current pandemic alone. From January 1998 to December 2001, 193 cases of pulmonary tuberculosis (PTB) and 30 . Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that has protean manifestations and follows a relapsing and remitting course. Improving diagnostics of celiac disease. Author Affiliations. 1, Charles P. Orsay M.D. The clinical presentation is protean ranging from diffuse symptoms such as chronic headaches, neck stiffness, cognitive decline, and seizures to focal mechanical symptoms due to nerve compression including optic neuropathy, cranial nerve palsies, and cortico-spinal sensorimotor deficits [ 3, 7 ]. More than 90% of cases of SLE occur in women, frequently starting at childbearing age. The clinical manifestations of SCD are protean. Abstract. Uncovering the protean clinical manifestations. the importance of using both polymerase chain re-action (PCR) to amplify VZV DNA in . The ACE2 receptor the virus uses to enter cells is common in many organs, plus there were extrapulmonary manifestations with severe acute respiratory syndrome (SARS), another pandemic caused by a zoonotic coronavirus almost 20 years ago. Protean Manifestations and Diagnostic Challenges Including Discordance Between Electrodiagnostic-Radiologic Studies in. Author Affiliations. The protean manifestations of Legionnaires' disease are described in an analysis of 12 sporadic cases. Medical Progress from The New England Journal of Medicine — The Cytomegaloviruses: Ubiquitous Agents with Protean Clinical Manifestations — (Second of Two Parts) 2 & Herand Abcarian M.D. Founded in 1994 as part of a humanitarian operation in Rwanda, Autremonde as such belongs to the multifarious and protean world of non-governmental organisations. Protean manifestations of pheochromocytoma may simulate many conditions, some of which may have elevated plasma and urine catecholamines and their metabolites. CIT can broadcast your seminar, conference or meeting live to a world-wide audience over the Internet as a real-time streaming video. It has protean manifestations and at times,poses significant diagnostic challenges to both the radiologist and the treating physician. The Protean Manifestations of Granular Cell Tumor of the Breast The Protean Manifestations of Granular Cell Tumor of the Breast Lee, Su‐Ju; Mahoney, Mary C. 2011-03-01 00:00:00 Granular cell tumor (GCT) of the breast is an uncommon, but important entity because of its tendency to mimic breast carcinoma. They are of concern to urologists and general surgeons alike because of their often protean clinical manifestations. Hematology; Research output: Contribution to journal › Comment/debate › peer-review. Pulmonary edema is only one of several manifestations of altitude illness. Waldenström macroglobulinemia (WM) is an indolent lymphoma in which malignant monoclonal plasmacytoid lymphocytes infiltrate bone marrow and visceral organs, and hypersecrete a monoclonal immunoglobulin M (IgM). During the past decade, however, their prevalence, protean manifestations, and importance as a public health problem have received ever-increasing attention. It is often diagnosed following an incidental finding of an IgM paraprotein on a blood test. These conditions can be difficult to recognize, especially as several can occur without rash. Richard L. Nelson M.D. Thus, in such patients, the clinician should determine whether there is a history of recent zoster or varicella rash and, if affirmative, then virological analysis for VZV should be done. Our clinical experience enables us to concur with the recommendations of Agatstein and Stabile' concerning their management. Protean Manifestations of Gastrointestinal Tuberculosis Y Ismail, FRCP, A Muhamad, M. Surg. Skip to main content Accessibility help We use cookies to distinguish you from other users and to provide you with a better experience on our websites. The burden of celiac disease alleviates with gluten-free diet. Protean clinical manifestations and diagnostic challenges of human brucellosis in adults: 16 Years' experience in an endemic area July 2006 Journal of Medical Microbiology 55(Pt 7):897-903 The Protean Manifestations of GATA2 Deficiency Across the Lifespan. The protean clinical manifestations of celiac disease RJ Farrell, CP Kelly N Engl J Med 2002; 346:183 Can presenting at any age to any medical specialty #1 Consider a diagnosis of celiac disease COP YRIGHT Multidetector computerized tomography (CT) is an essential tool in identifying the etiology, pathogenesis, protean manifestations of systemic tuberculosis, and ultimately deciding the course of . GCT is a tumor of Schwann cell origin. A 19-year-old boy presented with a gradually increasing head swelling. Pearson syndrome illustrates many features of abnormal mitochondrial function and genetics. The protean manifestations of familial polyposis coli. Overview; Fingerprint; Original language: English (US) Pages (from-to) 824-825: Number of pages: 2: Journal: Mayo Clinic proceedings: Juliana Perez Botero, Mrinal M. Patnaik. It has a wide spectrum of non­ specific symptoms and signs. . Charles S. Houston, MD. Abstract. protean manifestations of this infrequent disease. They are of concern to urologists and general surgeons alike because of their often protean clinical manifestations. E-mail address: [email protected]. disease produced by VZV vasculopathy, as well as. The Protean Manifestations of GATA2 Deficiency Across the LifespanAir date: Wednesday, December 11, 2013, 3:00:00 PMRuntime: 01:07:23 Description: The NIH Di. The patients presented with . This pictorial essay aims to acquaint the radiologist with the varied imaging spectrum of intracranial tuberculosis . In addition to previously reported manifestations, massive uterine bleeding and hypothyroidism were. The protean manifestations of varicella-zoster virus vasculopathy Varicella-zoster virus (VZV) vasculopathy in the central nervous system (CNS) affects large and small cerebral vessels. Leptospirosis is a zoonosis with protean clinical manifestations caused by pathogenic spirochetes of the genus Leptospira. While mumps is easily suspected i. Intracranial tuberculosis continues to be a serious problem in both the developing and developed world, with significant morbidity and mortality. Many of these patients, however, manifest soft . High Altitude Illness: Disease With Protean Manifestations. Objectives: Description of the clinical manifestations, endoscopic findings and histological features in a cohort of patients with SRUS. Correspondence to: David K. Lorance, MD, University of Vermont Medical Center, Burlington, VT 05401. L Gore 1,2, J Ess 1, MA Bitter 3, L McGavran 4,5, L Meltesen 4, Q Wei 2,4 & Splenic infarction leads to functional hyposplenism early in life, which in turn increases the risk of infection. Despite the increasing frequency with which . Kedah Medical Centre, Alor Setar Introduction The abdomen is a common site ofextrapulmonary tuberculosis. springer Michael Shishman is considered a vain, aggressive, and opportunistic ruler, whose Protean foreign policy perhaps contributed to the battle that put an end to . Uncovering the protean clinical manifestations. Epub 2020 Nov 12. Thus, in such patients, the clinician should determine whether there is a history of recent zoster or varicella rash and, if affirmative, then virological analysis for VZV should be done. Jacqueline J. Greene, Ilka C. Naumann, Janet M. Poulik, Kevin T. Nella, Lindsay Weberling, Jeffrey P. Harris, Akihiro J. Matsuoka Protean manifestations of Proteus syndrome. Fanconi Anemia—Protean Manifestations of Defective DNA Repair. The protean neurologic manifestations of varicella-zoster virus infection REVIEW ABSTRACT Multiple neurologic complications may follow the reactivation of varicella-zoster virus (VZV), including herpes zoster (also known as zoster or shingles), postherpetic neuralgia, vasculopathy, myelitis, necrotizing CASE REPORT Open Access The protean manifestations of central nervous system IgG4-related hypertrophic pachymeningitis: a report of two cases Peter Y. M. Woo1*, Ben C. F. Ng1, June H. M. Wong2, Oliver K. S. Ng3, Timothy S. K. Chan3, Ngai-Fung Kwok4 and Kwong-Yau Chan1 Abstract It produces protean manifestations ranging from head to toe, wreaking seemingly indiscriminate havoc on multiple organ systems including the lungs, heart, brain, kidney, and vasculature. 1990; 113(5):385-91 (ISSN: 0003-4819) Protean clinical manifestations in children with leukemias containing MLL-AF10 fusion. Jacqueline J. Greene, Ilka C. Naumann, Janet M. Poulik, Kevin T. Nella, Lindsay Weberling, Jeffrey P. Harris, Akihiro J. Matsuoka One patient presented with a maternal history of diuretic use, and developed asymptomatic . AU - Guillen, Denisse E. AU - Pinargote, Paulette M. Thirty-four adult patients with portomesenteric venous occlusion (PVO) were reviewed. Protean manifestations of COVID-19: "Our ignorance is profound" . Dermatology Department, St Mary's Hospital, Imperial College Healthcare Trust, London, UK. Baro-reflex failure, postural. T1 - The silent sinus syndrome. While this may sometimes be true, more . The silent sinus syndrome: protean manifestations of a rare upper respiratory disorder revisited. Skip Navigation. DIFFERENTIAL DIAGNOSIS — Given the protean manifestations of systemic lupus erythematosus (SLE), the differential diagnosis is correspondingly broad. Pseudoxanthoma Elasticum: An Underdiagnosed Genetically Heterogeneous Disorder with Protean Manifestations Lawrence K. Altman, Philip J. Fialkow, Frank Parker, Richard W. Sagebiel Research output : Contribution to journal › Article › peer-review High Altitude Illness: Disease With Protean Manifestations. Request PDF | Protean Manifestations of Gastrointestinal Tuberculosis | We present 11 cases to illustrate the protean presentations of gastrointestinal tuberculosis. The prevalence of celiac disease increases but the majority of the patients still remain undiagnosed. Background: Solitary Rectal Ulcer Syndrome (SRUS) is a relatively uncommon, benign condition which clinically, endoscopically and histologically can mimic many conditions including carcinoma of the rectum and inflammatory bowel disease. Head and Neck The head and neck are involved in 90% of pa-tients with GPA, being the areas of presenting symptoms in 73% of them, and the sites most commonly affected are the nose, eyes, ears, and maintenance (next 24-48 months) aimed at preventing disease relapse, based on therapy with In addition, the multiorgan protean manifestations of mycoplasma infection are discussed in terms of the role that mycoplasma adhesins may play in molecular mimicry, postinfectious autoimmunity, and immune-mediated damage. « A Pandemic Puppy "Not Begrudging" » Protean Manifestations November 21, 2020 by mountainmornings Let's face it, this virus is out of control. 2 Diseases of the Colon & Rectum volume 31, pages 699-703 (1988)Cite this article TY - JOUR. Acquired syphilis can be divided into primary, secondary, latent, and tertiary stages. Seven previously unrecognized cases were found through family studies. The tethered spinal cord: its protean manifestations, diagnosis and surgical correction Abstract 31 children with spina bifida occulta who have presented with back pain, scoliosis, a progressive neurological deficit involving lower limbs or a neurogenic bladder have been found to have a tethered spinal cord. Among the protean neurological manifestations of VZV vasculopathy are aneurysm, subarachnoid and cerebral haemorrhage, arterial ectasia, and carotid dissection. 2021 Mar;133(2):250-252. doi: 10.1080/00325481.2020.1840830. One patient presented with a temporoparietal mass, the second, a progressive dementia, the third suggested herpes simplex . Repeated venepunctures, injection of insoluble substances and needle sharing habits in intravenous drug users result in complications leading to admissions under various medical specialities. Five tissue-proven cases emphasise the protean manifestations of this disease and the difficulties encountered in reaching a diagnosis. In 11 with hepatic cirrhosis, PVO was usually heralded by worsening ascites often with varix hemorrhage; mortality was high. The protean manifestations of RASA1 gene mutation P. Nicholson. For instance, I just saw my amazing hair stylist Chase for a splash of magenta pink, because why go halfway when coloring your hair? NIH VideoCasting. The authors declare no conflict of interest. Abstract. Life-long gluten free diet is challenging. . Two forms of the disease have been delineated. Most glaring was the discrepancy in length of the lower limbs with the right being . Four with isolated portal block had varix . Nine patients examined by arteriography were shown to have mycotic aneurysms involving the thoracic aorta, subclavian artery, renal artery, middle cerebral artery, hepatic artery, and splenic arter. Large-vessel disease is most common in immunocompetent individuals, whereas small-vessel disease usually develops in immunocompromised patients. the protean clinical manifestations of neurological. Charles S. Houston, MD. According to the ancient Greeks, Proteus was the shepherd who looked after Poseidon's sea creatures. Acute fluconazole toxicity: a case presenting with protean manifestations including systemic and neurologic symptoms Postgrad Med. E-mail: [email protected]. The growing awareness of COVID's protean manifestations is evident in Medscape's Consult forum, an online community where physicians and medical students share information and seek advice; there's been over 200 COVID-19 cases and questions since January. Syphilis is a sexually transmitted disease with protean manifestations resulting from infection by Treponema pallidum. 1997; 19(4):279-86 (ISSN: 1077-4114) Kerr DS. Protean refers to Proteus, the mythologic master of disguise. 2, Russell K. Pearl M.D. This essay explores the hypothesis that COVID-19, particularly in the later complicated stages, represents an endothelial disease. Determined not to share his knowledge, he changed his shape to avoid attention. While it is beyond the scope of this review to provide a comprehensive list of all possible alternative diagnoses, we present several here. Ann Intern Med. Life-long gluten free diet is challenging. Five tissue-proven cases emphasise the protean manifestations of this disease and the difficulties encountered in reaching a diagnosis. We would like to show you a description here but the site won't allow us. Protean manifestations of mitochondrial diseases: a minireview. The prevalence of celiac disease increases but the majority of the patients still remain undiagnosed. A retrospective review of 26 cases from Korea. Pulmonary edema is only one of several manifestations of altitude illness. From the Department of Epidemiology and Environmental Health, University of Vermont College of Medicine, Burlington. Thirty-four adult patients with portomesenteric venous occlusion (PVO) were reviewed. Classically, the symptoms of neonatal hypoglycemia have been referable to central nervous system dysfunction, with seizures described in nearly all patients. Denisse E Guillen 1, Paulette M Pinargote 1 & Juan C Guarderas 2 Clinical and Molecular Allergy volume 11, Article number: 5 (2013) Cite this article In 11 with hepatic cirrhosis, PVO was usually heralded by worsening ascites often with varix hemorrhage; mortality was high. It is systemic early from the outset, the primary pathology being vasculitis. Synonyms for the disease include Weil's disease, Weil-Vasiliev disease, Swineherd's disease, rice-field fever, waterborne fever, nanukayami fever, cane-cutter fever, swamp fever, mud fever, Stuttgart disease, and Canicola . The protean manifestations of hemorrhagic fever with renal syndrome. The growing awareness of COVID's protean manifestations is evident in Medscape's Consult forum, an online community where physicians and medical students share information and seek advice; there's been over 200 COVID-19 cases and questions since January. Ultrasound and possibly CT are useful methods to document the presence of urachal CyStS.11,18,22,23 The . Nine probands with pseudoxanthoma elasticum (PXE) and 65 of their relatives underwent clinical and histological investigation. The protean manifestations of childhood narcolepsy and their misinterpretation - Volume 48 Issue 4. Protean manifestations of intravenous drug use. At least with SARS, "many organs . Scrub typhus is a common infectious disease in tropical countries but has protean manifestations. Improving diagnostics of celiac disease. And vaso-occlusion, which can lead to acute and chronic pain and tissue ischemia infarction. 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Seminar, conference or meeting live to a world-wide audience over the Internet as real-time.: Description of the clinical manifestations of altitude illness Description of the patients still remain undiagnosed who! Poses significant diagnostic challenges to both the radiologist with the recommendations of Agatstein and &... This disease and the difficulties encountered in reaching a diagnosis cohort of patients with SRUS share knowledge... Vasculitis of unknown cause restricted to vessels of the clinical manifestations, findings.
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